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If this pathway slows down, oxidative stress, chronic inflammation, and even neurological issues can appear

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Mol Cell (2001) 7(6):116576.10.1016/S1097-2765(01)00265-9 128 HuangCJHaatajaLGurloTButlerAEWuXSoellerWCet alInduction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

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It is ideal for use in low concentrations of 2-5% in cosmetic products